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RESEARCH

injury, further damaging an already injured Center, Navicent Health can be the first Level corporations contributing to Medcen's
Research and Education Fund.
brain. However, there is really not any 1 Trauma Center to speak to this topic. We are
“High quality medical care is built upon years
significant literature that speaks to optimistic that our research can of effort by medical professionals investigating
the causes of and potential treatments for
how long is long enough for improve the care of patients with disease. There is still much work to be done
and philanthropic support of this work is vital,”
active fever prevention. We “I am hopeful that traumatic brain injury. The said Jack Schwartz, Chief Development Officer
are hoping that by ability to complete this project for Medcen.

following the trend of a would not be possible without For more information on Medcen Community Health
Foundation, Navicent Health or to find out how you
particular brain we will find the answers the Medcen grant, and I am can play a role in funding local research, please visit
NavicentHealth.org and choose “Give Back.” Medcen
neuromarker, we will so thankful that Navicent will accept applications for Research and Education
Grants May 1 – July 1, 2015.
identify a time period and be able to contribute Health not only supports
in which we see a best care for patients, but

decrease in the to the knowledge base,” also supports care for
production of brain patients worldwide through

inflammation in such advancements in research.”

patients. If we are able to Dr. Amy Christie. The grant program would not be
narrow down a time period

in which the brain possible without local support.

inflammation tends to subsides, Since 1998, Medcen has contributed

we could use this as a potential more than $1.2 million to research and

indicator as to how long we should be education projects. Many of the awarded

preventing fever in traumatic brain injury,” said grants are funded in joint partnership between

Dr. Christie. “We are hoping that Medical Medcen and MUSM, with individuals and

A Sample of Research Happening Now

1 “The predictive value of neuromarker S- 2 “Investigating the role of TRPV4 in 3 “Demographic Distinctions in Immune
100B protein in determining optimal asthma.” Mechanisms of Heart Failure”

duriation of targeted normothermia in a) Research Team: Qihai Gu, MD; a) Research Team: Peter N. Uchakin,
Sabry A. Gabriel, MD; Carolyn A PhD; Ahmed I. Shah, MD; Hemant
traumatic brain injury.” Gilbert, BS; Kristen Kettelhut, Goyal, MD
MUSM student
a) Research Team: Amy Christie, MD; b) Amount: $20,000 divided by
Dennis Ashley, MD; Richard Rowe, b) Amount: $20,000 divided by Medcen and MUSM
MD; Joey Jarrard, MD Medcen and MUSM
c) Summary: Pro- and anti-cytokines
b) Amount: $20,000 from Medcen c) Summary: Recent research indicates are released by specific immune cells
that asthma occurs through and play a key regulatory role in the
c) Summary: Trauma critical care bidirectional signaling between the development of all inflammatory
physicians will conduct blood tests immune and nervous systems. reactions. If, due to genetic and
to determine the levels of S-100B in Researchers hypothesize that social factors, a person's immune
traumatic brain injury patients, with receptor TRPV4 plays a direct role cells fail to balance these cytokines,
hopes of determing how long fever in this communication. By studying it could damage any organ,
should be prevented in such patients. TRPV4, researchers hope to discover specifically the heart. Researchers
new information in the development are investigating the demographic
of asthma and offer new therapeutic distinctions of underlying immune
strategies for treatment. molecular mechanisms that may lead
to heart failure.

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